USMLE High Yield Rating List for Genetics


Correction: I said & wrote “Post-Translational Mods” when I really meant post-TRANSCRIPTIONAL modifications. Thanks to Sean Typher for point out the typo in the comments!

Expect about 16 genetics questions on the exam

 

10 – Autosomal Recessive Inheritance

9 – X Linked Recessive Inheritance

9 – Pedigrees

7 – Post-Transcriptional Modifications

6 – Translation

6 – Trinucleotide Repeat Expansion

5 – Mitochondrial Inheritance

5 – Tuberous Sclerosis

4 – Epigenetics

4 – Autosomal Dominant Inheritance

4 – Lesch Nyhan

3 – DNA Replication

3 – Imprinting, Angleman & Prader-Willi

3 – Polygenic Inheritance

3 – Neurofibromatosis

3 – Down Syndrome

2 – Variable Expressivity

2 – Variable Expressivity

2- Mosaicism

2 – Pleiotropy

2 – Incomplete Penetrance

2 – Von  Hippel Lindau

 

No Yield:

  • Nucleotide & DNA/RNA Structure
  • Ligase, Telomerase, Helicase, Primase ….
  • Okazaki Fragments & the process of transcription
  • DNA Repair Mechanisms & Related Diseases
  • Gene Regulation
  • Specifics about Protein Synthesis
  • Meiosis & Mitosis
  • X-Linked Dominant
  • Hardy-Weinberg Calculations
  • Uniparental disomy
  • Locus heterogeneity
  • Pyrimidine Synthesis
  • Purine Synthesis
  • Orotic Aciduria
  • Sturge Weber Syndrome
  • Osler-Weber-Rendu Syndrome
  • Ataxia Telangiectasia
  • Cri du Chat
  • Edwards
  • Patau
  • Friedrichs Ataxia
  • Myotonic dystrophy

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